Two disease models (the prevalence and population attributable risk models) are provided in SeqSIMLA. Alternatively, a penetrance table can be provided directly to SeqSIMLA. SeqSIMLA can also simulate quantitative traits while accounting for correlations in families.
To cite SeqSIMLA2, please use:
Chung RH, Tsai WY, Hsieh CH, Hung KY, Hsiung CA, Hauser ER. 2014. SeqSIMLA2: Simulating Correlated Quantitative Traits Accounting for Shared Environmental Effects in User-Specified Pedigree Structure. Genetic Epidemiology. In press.